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6 Supplements That Fight Inflammation

Inflammation can occur in response to trauma, illness and stress.
However, it can also be caused by unhealthy foods and lifestyle habits. Anti-inflammatory foods, exercise, good sleep and stress management can help. In some cases, getting additional support from supplements may be useful as well.

Here are 6 supplements that have been shown to reduce inflammation in studies.

1. Alpha-Lipoic Acid

Alpha-lipoic acid is a fatty acid made by your body. It plays a key role in metabolism and energy production.

It also functions as an antioxidant, protecting your cells from damage and helping restore levels of other antioxidants, like vitamins C and E .

Alpha-lipoic acid also reduces inflammation. Several studies show that it reduces the inflammation linked to insulin resistance, cancer, liver disease, heart disease and other disorders.

Recommended dosage: 300–600 mg daily. No issues have been reported in people taking 600 mg of alpha-lipoic acid for up to seven months.

Potential side effects: None if taken at the recommended dosage. If you also take diabetes medication, then you may need to monitor your blood sugar levels.

Not recommended for: Pregnant women.

BOTTOM LINE:Alpha-lipoic acid is an antioxidant that can reduce inflammation and may improve the symptoms of certain diseases.

2. Curcumin

Curcumin is a component of the spice turmeric. It provides several impressive health benefits.

It can decrease inflammation in diabetes, heart disease, inflammatory bowel disease and cancer.

Curcumin also appears to be very beneficial for reducing inflammation and improving symptoms of osteoarthritis and rheumatoid arthritis.

One randomized controlled trial found that people with metabolic syndrome who took curcumin had significantly reduced levels of the inflammation markers CRP and MDA, compared to those who received a placebo.

Recommended dosage: 100–500 mg daily, when taken with piperine.

Potential side effects: None if taken at the recommended dosage.
Not recommended for: Pregnant women.

BOTTOM LINE:Curcumin is a potent anti-inflammatory supplement that reduces inflammation in a wide range of diseases.

3. Fish Oil

Fish oil supplements contain omega-3 fatty acids, which are vital to good health.

They can decrease the inflammation associated with diabetes, heart disease, cancer and many other conditions.

Two especially beneficial types of omega-3s are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). DHA, in particular, has been shown to have anti-inflammatory effects that reduce cytokine levels and promote gut health. It may also decrease the inflammation and muscle damage that occur after exercise.

Recommended dosage: 1–1.5 grams of omega-3s from EPA and DHA per day. Look for fish oil supplements with undetectable mercury content.

Potential side effects: Fish oil may thin the blood at higher doses, which can increase bleeding.

Not recommended for: People taking blood thinners or aspirin, unless authorized by their doctor.

BOTTOM LINE:Fish oil supplements containing omega-3 fatty acids can improve inflammation in several diseases and conditions.

4. Ginger

Ginger root is commonly ground into powder and added to sweet and savory dishes.It’s also commonly used to treat indigestion and nausea, including morning sickness.

Two components of ginger, gingerol and zingerone, may reduce the inflammation linked to colitis, kidney damage, diabetes and breast cancer.

When people with diabetes were given 1,600 mg of ginger daily, their CRP, insulin and HbA1c levels decreased significantly more than the control group (39Trusted Source).

Recommended dosage: 1 gram daily, but up to 2 grams is considered safe (43Trusted Source).

Potential side effects: None at the recommended dosage. However, higher dosages may thin the blood, which can increase bleeding.

Not recommended for: People who take aspirin or other blood thinners, unless authorized by a doctor.

BOTTOM LINE:Ginger supplements have been shown to reduce inflammation, as well as muscle pain and soreness after exercise.

5. Resveratrol

Resveratrol is an antioxidant found in grapes, blueberries and other fruits with purple skin. It is also found in red wine and peanuts.

Resveratrol supplements may reduce inflammation in individuals with heart disease, insulin resistance, gastritis, ulcerative colitis and other conditions.

Recommended dosage: 150–500 mg per day.

Potential side effects: None at the recommended dosag.

Not recommended for: People who take blood thinning medications, unless approved by their doctor.

BOTTOM LINE:Resveratrol may reduce several inflammatory markers and provide other health benefits.

6. Spirulina

Spirulina is a type of blue-green algae with strong antioxidant effects. Studies have shown that it reduces inflammation, leads to healthier aging and may strengthen the immune system.

Although most research to date has investigated spirulina’s effects on animals, studies in elderly men and women have shown that it may improve inflammatory markers, anemia and immune function.

Recommended dosage: 1–8 grams per day, based on current studies. Spirulina has been evaluated by the US Pharmacopeial Convention and is considered safe.

Potential side effects: Aside from allergy, none at the recommended dosage.

Not recommended for: People with immune system disorders or allergies to spirulina or algae.